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Innovative Chemistry

Alexander Dömling
ERA Chair
E-mail alexander.domling@upol.cz
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The Innovative Chemistry group will be established on the basis of a grant awarded within the Horizon Europe ERA Chairs Call. During the course of the next five years, CATRIN will be implementing an absolutely unique project entitled ACCELERATOR, the aim of which is to bring together the world-renowned professor, inventor and innovator, Alexander Dömling, as the ERA Chair, and CATRIN’s all three divisions, merging them into a unique scientific ecosystem.

The Innovative Chemistry group focuses on developing a fast, efficient and partially automated synthesis technology platform suited to optimize compound properties in an (semi)automated, miniaturized and accelerated fashion with the help of inhouse developed generative artificial intelligence algorithms. The technology platform with the name of AMADEUS will be applied to research and development questions in medicinal chemistry, plant enhancement biology and nano material discovery—the three CATRIN’s divisions. The fundamental challenge of this research arises from the equation automation + miniaturization = acceleration, which is successfully applied in many technologies and research area. However, synthetic chemistry is largely believed not to be automatable. Miniaturization together with automation will increase the throughput and gain of ‘big data’ to reduce costs, energy and waste. Hence, automation and miniaturization considerably contribute to the Sustainable Development Goals of United Nations and goals set up in the European Green Deal and will dramatically decrease the environmental footprint of future chemistry.

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